XDR-TB in South Africa is largely spread person-to-person, not by failure of drug treatment

February 26, 2015 7:41 AM

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The vast majority of people with extensively drug-resistant tuberculosis (XDR-TB) diagnosed in the world’s most extensive outbreak have acquired their infection from another person, not as the result of the failure of treatment for multi-drug resistant strains of tuberculosis (MDR-TB), N Sarita Shah told the Conference on Retroviruses and Opportunistic Infections in Seattle on Wednesday.

Kwazulu-Natal province in South Africa has been the setting for a large outbreak of XDR TB since 2006, when cases first began to be identified. XDR TB is defined as a form of TB that is resistant to isoniazid and rifampin, plus any fluoroquinolone and at least one of three injectable second-line dru...

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