Victoza Lowers Glucose in Genetic Form of Diabetes

June 15, 2014 9:48 PM

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SAN FRANCISCO -- Liraglutide (Victoza) works roughly as well as standard sulfonylurea treatment for an inherited type of diabetes but with less hypoglycemia, a small trial showed.

The GLP-1 receptor agonist cut glucose levels somewhat less than glimepiride (Amaryl) but without a significant difference (-1.6 versus -2.8 mmol/L, P=0.624) in 16 patients with maturity-onset diabetes of the young caused by a mutation in the hepatocyte nuclear factor 1-alpha gene, known as MODY3.

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