Smokers with genetic variant likely to smoke longer, get cancer sooner, study finds

April 15, 2015 7:30 PM

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Smokers with genetic variant likely to smoke longer, get cancer sooner, study finds

New research has pinpointed a specific genetic variation that may cause smokers to stick with the habit longer than smokers who don’t have the variant. The research, published in the Journal of the National Cancer Institute, also indicated that smokers with the genetic variant are more likely to be diagnosed with lung cancer at an earlier age.

Researchers at Washington University School of Medicine in St. Louis analyzed 24 studies involving more than 29,000 smokers of European ancestry. They concluded that smokers with a particular variation in the nicotine receptor gene, CHRNA5, were more likely to continue smoking for an average of four...

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