Slowdown of brain's waste removal system could drive Alzheimer's

March 17, 2015 5:29 PM

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Slowdown of brain's waste removal system could drive Alzheimer's

Since it was first identified more than a century ago, we still have no cure for Alzheimer’s disease. Among the various avenues that researchers have been working on to try and understand the causes and potential treatments for the disease, the role of blood vessels has been increasingly a focus – and in particular the “blood-brain barrier”, a protective layer of cells that regulates what can enter the brain through the blood.

The brain has a dense network of blood vessels, which if stretched end-to-end would cover more than 5,000 football pitches. However, unlike the blood vessels in other parts of the body, these vessels restrict which things can enter the brain from the blood stream. It does that by forming a physical ...

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