Once again Angelina Jolie Pitt made headlines with her New York Times op-ed article "Diary of a Surgery" addressing her decision to undergo prophylactic surgery to remove her ovaries and fallopian tubes. She chose to have the operation after her physician informed her that inflammatory markers from a test may point to ovarian cancer. Jolie Pitt's mother, grandmother, and aunt all lost their lives to cancer.
In 2013, Jolie Pitt revealed her decision to undergo a prophylactic bilateral mastectomy with reconstruction as a safeguard against breast cancer. As a carrier of the BRCA1 gene mutation she had an estimated 87 percent risk of breast cancer and 50 percent risk of ovarian cancer.