In a single gene, a path to fight heart attacks

June 19, 2014 4:07 AM

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In a single gene, a path to fight heart attacks

Two major studies by leading research groups published on Wednesday independently identified mutations in a single gene that protect against heart attacks by keeping levels of triglycerides — a kind of fat in the blood — very low for a lifetime.

These findings are expected to lead to a push to develop drugs that mimic the effect of the mutations, potentially offering the first new class of drugs to combat heart disease in decades, experts say. Statins, which reduce LDL cholesterol, another cause of heart disease, became blockbusters in the ...

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