A routinely dosage of Aspirin not congenial for older hearts says a Japanese Study

November 17, 2014 11:08 PM

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A routinely dosage of Aspirin not congenial for older hearts says a Japanese Study

Although once quite popular, the use of aspirin to prevent a first heart attack has grown less popular in recent years as evidence has accumulated that the small benefits are outweighed by the increased risk of bleeding. Now a large trial from Japan has once again failed to provide any evidence to support the use of routine aspirin in high risk elderly people to prevent a first cardiovascular event.

The Japanese Primary Prevention Project (JPPP), presented at the American Heart Association meeting in Chicago and published simultaneously in JAMA, enrolled patients between 60 and 85 years of age with hypertension, dyslipidemia, or diabetes. The open label study randomized 14,464 patients to aspir...

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