A Risky Addition to Post-MI Antithrombotics | Medpage Today

February 25, 2015 7:03 PM

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A Risky Addition to Post-MI Antithrombotics | Medpage Today

Adding a non-steroidal anti-inflammatory drug (NSAID) to antithrombotic therapy after a heart attack might boost bleeding risk, even if taken briefly as a painkiller, an observational study suggested, supporting guidelines warning against the combo.

Adding another NSAID atop recommended dual antiplatelet therapy with aspirin and clopidogrel (Plavix) was associated with a significant 2.41-fold higher risk of bleeding requiring hospitalization than the same regimen without an NSAID, Anne-Marie Schjerning Olsen, MD, PhD, of Copenhagen University H...

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