Prostate cancer drug innovation prolongs life by more than a year in worst cases

June 2, 2014 1:47 PM

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Prostate cancer drug innovation prolongs life by more than a year in worst cases

Christopher J. Sweeney of Dana-Farber Cancer Institute's Lank Center for Genitourinary Oncology said currently, men newly diagnosed with prostate cancer which spread widely and whose cancer depends on male hormones to grow, were started on hormone-blocking medications -- androgen deprivation therapy. Most tumors eventually outgrow their need for hormones and the cancer progresses, and only then do patients begin chemotherapy, Sweeney explained.

The trial involved 790 men newly diagnosed with metastatic prostate cancer. Half were randomized to receive ADT alone or ADT with docetaxel --Taxotere -- over 18 weeks. In the ADT-only group, 124 men were given docetaxel when their cancer worsened. In the ADT-plus-docetaxel group, 45 patients whose ...

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