Patient Zero believed to be sole source of Ebola outbreak

October 9, 2014 7:49 PM

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Patient Zero believed to be sole source of Ebola outbreak

One glaring fact from the latest report on the Ebola outbreak is that five of the many study authors are dead, killed by the disease that is roiling west Africa. The new analysis, published in the August 29 issue of Science, reveals that the current Ebola outbreak stemmed from an earlier initial leap from the wild into humans, rather than the virus repeatedly jumping from a natural reservoir—perhaps infected animals—to humans. By essentially sketching out a high-tech molecular family tree, researchers concluded that the virus spreading in Sierra Leone and nearby countries is the descendent of an original Ebola viral jump, and not new versions of the pathogen that are being repeatedly introduced into the human population. That means the public health response to this outbreak—which focuses on tracking and treating those who have been exposed to people with Ebola, rather than attempting to keep people away from potential animal carriers—has been the right strategy.

That conclusion comes from a sweeping analysis of 99 Ebola virus genome sequences that comprise some 70 percent of the Ebola patients diagnosed in Sierra Leone in late May to mid-June. The virus samples were extracted from the blood of 78 patients early in Sierra Leone’s outbreak. And the work indic...

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