Obesity Gene Weightier, Depending on Year of Birth

December 30, 2014 3:12 PM

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Obesity Gene Weightier, Depending on Year of Birth

Disentangling nature and nurture just got more complicated. Now it seems that time, too, may be involved in gene/environment interactions, say scientists who evaluated the effects of a gene variant long associated with obesity risk. The variant, which affects the FTO gene, appears to have more or less impact depending on a person’s year of birth.

The FTO variant has the greatest impact on body mass index (BMI) for those born after 1942. In fact, the impact was found to be twice as strong as reported in previous studies, which were confined to less wide-ranging age cohorts than the current study, which delved into information collected by the...

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