Now a drug that could prevent migraine attacks

April 23, 2014 4:43 AM

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Researchers have developed drugs that are aimed at preventing migraine attacks from occurring, rather than stopping the attacks once they have started. These studies are the first to test monoclonal antibodies for the prevention of migraine, and both are directed against a relatively new target in migraine prevention, the calcitonin gene-related peptide, or CGRP. Both are phase II studies, meaning larger studies are needed to confirm the results. (Read: Suffering from a migraine? Try magnetic therapy)

One study involved 163 people who had migraine from five to 14 days per month. They received either a placebo or a single IV dose of a drug called ALD403 and then were followed for 24 weeks. Those who received the drug had an average of 5.6 fewer migraine days per month, a 66-percent decrease, compa...

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