Major Advance for Diabetes Stem Cell Therapy?

October 15, 2014 4:30 PM

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Last month, two papers reported successful transformation of human stem cells into insulin-producing beta cells that worked when they were implanted into diabetic mice. Both protocols aim to forge a significant population of beta cells in vitro, instead of transplanting cells that are not yet fully transformed, as is the case with one technology by ViaCyte currently headed to clinical trials.

Juan Dominguez-Bendala, PhD, of the Diabetes Research Institute at the University of Miami, is also working on solutions to create fully mature beta cells in vitro. In this contributed report, he provides context on the two papers and on the general landscape of stem cells in diabetes therapy.

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