Heart risk lowering gene mutation found, boosts interest in Zetia

November 14, 2014 7:11 AM

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Scientists from the Washington University School of Medicine in St. Louis, the Broad Institute at the Massachusetts Institute of Technology and Harvard, and other institutions have been able to discover rare gene mutation that causes naturally lower cholesterol levels and reduces people’s risk of heart disease by 50%. The mutation is very rare and just one in every 650 people carries that mutation.

This discovery could have huge implications for Zetia, a drug from Merck & Co. because it mimics these mutations. Though it has been on the shelves for a long time because of its ability to lower LDL (bad cholesterol), and has also earned federal approval for it, it was not known that it also cuts t...

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