Gene Marker IDs Aspirin Response, Predicts MI

July 3, 2013 7:31 PM

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Gene Marker IDs Aspirin Response, Predicts MI

A collection of 60 co-expressed genes -- called the Aspirin Response Signature (ARS) -- predicted both response to aspirin treatment and the risk of death or myocardial infarction among patients undergoing cardiac catheterization, researchers found.

The ARS was significantly associated with platelet function in two groups of healthy volunteers taking 325 mg of aspirin per day, and in a group of cardiology patients taking 81 mg of aspirin per day (P<0.05 for all), according to Deepak Voora, MD, of Duke University, and colleagues.

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