First-line metformin treatment decreased need for subsequent treatment in diabetes

October 27, 2014 8:05 PM

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First-line metformin treatment decreased need for subsequent treatment in diabetes

More than 40% of patients with diabetes do not start out their glucose-lowering regimen with metformin despite recommended guidelines, according to research published in the Journal of the American Medical Association Internal Medicine.

Initiating therapy with metformin was associated with reduced subsequent treatment intensification vs. other oral agents, without differences in hypoglycemia rates or other adverse clinical events, in a retrospective cohort study of insured Aetna members.

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