DOJ closes investigation into clinical trial for ticagrelor

August 20, 2014 3:57 AM

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The US Department of Justice has closed its investigation into the PLATO trial of ticagrelor, according to a press release from AstraZeneca.

PLATO included more than 18,000 patients with ACS across 43 countries and compared ticagrelor (Brilinta, AstraZeneca) with clopidogrel (Plavix, Sanofi Aventis/Bristol-Myers Squibb) when given in combination with aspirin and other standard treatment. According to the company, the DOJ does not intend ...

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