Current way of detecting gene mutations misses people at high risk of cancer

December 1, 2014 1:20 PM

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Current way of detecting gene mutations misses people at high risk of cancer

(Medical Xpress)—Research led by a University of Manchester academic on the BRCA gene mutation in the Jewish population shows that the current process of identifying people which relies on assessing someone's family history, misses half the people who have the mutation and are at risk of developing cancer.

Women carrying a BRCA 1 or 2 gene mutation have approximately a 15%-45% chance of getting ovarian cancer and a 45-65% chance of getting breast cancer. Women who know they are carriers can better manage their risk of developing cancer by enhanced screening or risk-reducing surgery.

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