CIRCUS Trial Results: Cyclosporine No Better than Placebo for Heart Failure Following PCI

August 30, 2015 6:30 PM

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According to trial results presented by Michel Ovize, MD, PhD, Louis Pradel Hospital and Claude Bernard University, Lyon, France, at ESC Congress 2015, treatment with cyclosporine was no better than placebo for patients who received percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).

Results from the CIRCUS (Does Cyclosporine Improve Clinical Outcome in ST Elevation Myocardial Infarction Patients) trial showed that treatment with cyclosporine 2.5 mg per kilogram prior to PCI “had no impact on a composite of all-cause death, hospitalization for - or worsening of - heart failure, ...

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