Invading glioblastoma cells may hijack cerebral blood vessels during early stages of disease progression and damage the brain's protective barrier, a study in mice indicates. This finding could ultimately lead to new ways to bring about the death of the tumor, as therapies may be able to reach these deadly cells at an earlier time point than was previously thought possible. This research, published in Nature Communications, was supported by the National Institute of Neurological Disorders and Stroke (NINDS), part of the National Institutes of Health.
Glioblastoma, a type of aggressive brain tumor, is one of the most devastating forms of cancer. These tumors spread quickly and are difficult to treat because the brain protects itself from foreign substances.