Blood Pressure Meds Tied to Lower ALS Risk

November 11, 2014 5:22 PM

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In a study involving the entire adult population of Taiwan, individuals with amyotrophic lateral sclerosis (ALS) were significantly less likely to have used so-called ACE inhibitors prior to diagnosis than otherwise similar individuals in the general population, researchers said.

Among people whose total ACE inhibitor exposure over a 4-year period exceeded 449.5 times the generally accepted daily dosage, the odds ratio for developing ALS in year five was 0.43 (95% CI 0.26-0.72) relative to nonusers of these medications, according to Charles Tzu-Chi Lee, PhD, of Kaohsiung Med...

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