Aspirin, Clonidine Don't Cut Postop MIs

March 31, 2014 10:05 PM

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WASHINGTON -- The search must continue for a therapy that will lessen the risk of myocardial infarction (MI) following noncardiac surgery, following disappointing results from a large randomized trial.

In the POISE-2 trial, neither aspirin nor clonidine -- versus placebo -- administered just before surgery reduced the rate of death or nonfatal MI in patients who were already at risk for vascular complications, according to two presentations at the American College of Cardiology meeting here.

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