And so it began ... USA TODAY's Cindy Clark tracks the evolution of Brangelina, which sparked when Brad Pitt and Angelina Jolie steamed up screens in 2005's 'Mr. and Mrs. Smith.' In January 2005, Pitt and Jennifer Aniston, his then-wife (they married in 2000), announced their separation. Two months later, Aniston filed for divorce, citing irreconcilable differences.
Angelina Jolie and Brad Pitt, dodging rumors of a romance, kept their distance as they promoted 'Mr. and Mrs. Smith' at ShoWest in Las Vegas in March 2005.