Amount of mitochondrial DNA predicts frailty and mortality

December 16, 2014 8:08 PM

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Amount of mitochondrial DNA predicts frailty and mortality

New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples' blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty and death from any cause 10 to 15 years before symptoms appear.

The investigators say their findings contribute to the scientific understanding of aging and may lead to a test that could help identify at-risk individuals whose physical fitness can be improved with drugs or lifestyle changes. A summary of the research was published online Dec. 4 in the Journal of...

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