Addition of insulin to metformin in Type 2 Diabetes may increase risk of mortality

June 10, 2014 9:31 PM

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1. The addition of insulin to metformin was associated with an increased risk of all-cause mortality and an increased grouped risk of all-cause mortality and myocardial infarction (MI) or stroke relative to the addition of sulfonylureas.

2. The addition of insulin versus sulfonylureas to metformin did not differ in terms of rates of associated acute myocardial infarction (MI) or stroke alone.

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