Adding Non-Statin Leads to Even Lower LDL

February 10, 2014 11:32 PM

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Adding other drugs to lower-intensity statin therapy can lower LDL cholesterol as well as or better than higher-intensity statin therapy, but the effects on long-term outcomes remain uncertain, a systematic review showed.

A low-intensity statin plus a bile acid sequestrant reduced LDL cholesterol levels by 0% to 14% more than moderate-intensity statin monotherapy in high-risk patients with hyperlipidemia, according to Kimberly Gudzune, MD, MPH, of Johns Hopkins University School of Medicine, and colleagues.

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